Page 75 - RESUME NOTE REMINDER

possible influence of age and gender parameters in the presence of thyroid

microcarcinoma in a patient cohort with non-autonomous thyroid disorders and
without cytological establishment of cancer who underwent total thyroidectomy.

Patients-methods: Between 1.1.2005 and 01.03.2010 186 patients (146 females/40

males) underwent total thyroidectomy because of nodular goiter in our Department.
The classification of patients in both genders was conducted in the following age-

groups: a=20–39 y, b=40-59 y, c=>60 y. Thyroid specimens were histopathologically
examined at the University Pathology Department for the establischment of the final

diagnosis of benignity or malignancy. Thyroid cancer cases were categorised in
relation to gender and age group.

Results: 32 patients (17.2%) were diagnosed with microcarcinoma (rate

females:males 2.2:1), while 154 patients (82.8%) were free of malignancy. The
incidence of thyroid cancer in male subjects was 25.0% (10/40) and mainly in the

subgroup of solitary nodule compared to multinodular goiter (41.67 vs 17.86%). The
respective cancer freguency in female subjects was 15.0% (22/146). The incidence

of microcarcinoma per age group was in males: a=4/9; 44.4%, b=1/15; 6.67% and
c=5/16; 31.25% (P=0.089). In females it was respectively: a=7/40; 17.5%, b=9/73;

12.3%, c=6/33; 18.2% (P=0.650).

Conclusions: Thyroid microcarcinoma shows an elevated incidence in males with
non-toxic goiter, especially in the age groups 20–39 y and >60 y. Total thyroidectomy

appears to be the therapeutic method of choice in men with indication of surgical
removement of an euthyroid goiter which belong to the above age groups. Contrarily,

there is no statistically significant variation of microcarcinoma incidence in women
with benign thyroid disorders in relation to age.

15. Baseline serum TSH and risk of thyroid microcarcinoma in non-toxic nodular thyroid
disease

Dimitrios Askitis, Eleni I Efremidou, Michael Karanikas, Gregory Tripsianis,

Alexandros

Polychronidis & Nikolaos Liratzopoulos

th
Ανακοινώθηκε στο 18 European Congress of Endocrinology. Germany, Munich, 28-
31 May 2016

75