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Kaplan Meier while the possible effect ofany parameter in survival rates, such as the

PD modality and the role of solution’s bio-compatibility, which was evaluated by using
Cox Regression analysis.

Results: The age of our patients, the gender and the coexistence of diabetes did

notdiffer between the CAPD and the CCPD group. The overall 5-year survival was 40%
forthe patients using CCPD and 29% for the patients using CAPD while the

cumulativesurvival using was statistical significantly higher in the group using CCPD
(Kaplan-Meier analysis, Log Rank test p¼0,006). Furthermore Cox Regression

analysis revealedthat age (p<0,001), the presence of diabetes (p<0,001), CAPD
modality (p¼0,006) aswell as the use of bioincompatible peritoneal dialysis solutions

(p¼0,014) were inde-pendent risk factors for the survival of peritoneal dialysis
patients.

Conclusions: These results indicate that the presence of diabetes and the choice

ofPD modality may influence the survival of peritoneal dialysis patients.
Furthermore,the use of new peritoneal dialysis solutions may improve the survival of

PD patientspossibly due to the decreased local and systemic effects induced by
AGEs and GDPs

18. Parathyroid hormone excess due to denosumab application and concomitant

parathyroid adenoma with an atypical scintigraphic pattern- a case report

2
2
1
3
Dimitrios Askitis , Michail Karanikas , Nikolaos Michalopoulos , Aphroditi Strataki &
3
Athanasios Zissimopoulos
Ανακοινώθηκε στο 21 European Congress of Endocrinology. Lyon, France
st
18-21 May 2019

Δημοσιευτηκε σαν E-Poster (P483) | DOI: 10.1530/endoabs.63.P483

Abstract

Introduction: Primary hyperparathyroidism comprises one of the major causes of
hypercalcaemia and is mostly due to solitary parathyroid adenoma. Denosumab is a

novel antiresorptive agent for osteoporosis treatment and has been associated with a
compensatory increase in PTH levels during the first months after injection, a fact

that may interfere in the diagnostic procedures when dealing with concomitant small
parathyroid adenomas without standard scintigraphic pattern.

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