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30. Matis GK, Chrysou OI, Silva D, Karanikas MA, Baltsavias G, Lyratzopoulos N, Baroutas S, Birbilis

TH. Prediction of Lumbar Disc Herniation Patients' Satisfaction with the Aid of an Artificial
Neural Network. Turk Neurosurg. 2016;26(2):253-9. doi: 10.5137/1019-5149.JTN.8492-

13.0.PMID: 26956822 [PubMed] [Scopus]

Abstract AIM: To identify key determinants of lumbar disc herniation (LDH) patients'
satisfaction and to evaluate the efficiency of an artificial neural network (ANN) model to

prognosticate satisfaction derived from the hospital stay in this specific patient group.

MATERIAL AND METHODS: A single item question was used to assess patient satisfaction.
Principal component analysis evaluated several aspects of care (15 items). An ANN
encompassed all variables and its prediction ability was tested. The ANN performance was

correlated to a binary logistic regression (BLR) model.

RESULTS: Higher levels of satisfaction were reported by females, older patients, Greeks, and

patients with elementary education staying in not rural areas. A history of a single previous
hospitalisation was correlated with more satisfaction. The accuracy of ANN was 96% for
satisfaction prediction outperforming the BLR model.

CONCLUSION: Satisfactory health services are influenced by sex, age, nationality, and number

of prior admissions. The selfperceived health state plays also a crucial role. The current study
is the first one reporting on the capability of an ANN to accurately predict the satisfaction

levels of LDH patients.

31. Ilias Karapantzos, Paul Zarogoulidis, Michail Karanikas, Vasilis Thomaidis, Charalampos
Charalampidis, Chrysa Karapantzou. A Focus on Current Molecular Pathways in Head and

Neck. Oncomedicine 2016, Vol. 1 2016;1:28-34. doi: 10.7150/oncm.16930

Abstract Early stages of head and neck cancer require concomitant administration of
chemotherapy and radiotherapy. Currently platinum, taxane and fluoruracil analogs are being

administered. On the other hand, for advanced stages extensive surgery is required. During the
last years, several molecular characteristics have been identified in the tissue of head and

neck squamous cell carcinoma, and novel treatment options are being pursued. In this review
we will elucidate these molecular pathways that could be used as a possible treatment.

32. Michail Karanikas, Ferdi Bozali, Vasileia Vamvakerou, Markos Markou, Zeinep Tzoutze Memet

Chasan, Eleni Efraimidou, Theodossis S. Papavramidis. Billiary tract injuries after lap

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