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response, partial response, stable disease and progressive disease were observed in 4 (15%),
12 (44%), 3 (11%) and 8 (30%) patients, respectively. The observed response rate was 59%, and
the disease control rate (complete response + partial response + stable disease) was 70%. At
the time of analysis, 6 patients were still alive and the median survival was 18.0 months. The
most common grade III/IV toxicities observed were neutropenia (5%), diarrhea (2%), palmar-
plantar erythrodysesthesia (2%) and neurotoxicity (1%). All other toxicities were mostly of
grade I/II and easily manageable.
CONCLUSION: The combination of docetaxel, oxaliplatin and capecitabine in the described
mode of administration represents a relatively active and well-tolerated regimen in patients
with advanced gastric cancer and warrants further evaluation.
12. Touzopoulos P, Zarogoulidis P, Mitrakas A, Karanikas M, Milothridis P, Matthaios D,
Kouroumichakis I, Proikaki S, Pavlioglou P, Katsikogiannis N, Constantinidis TC. Occupational
chemical burns: a 2-year experience in the emergency department. J Multidiscip Healthc.
2011;4:349-52. doi: 10.2147/JMDH.S25141. Epub 2011 Oct 3. PMID: 22096339 [PubMed]
[Scopus]
Abstract: Chemical burn injuries are a result of exposure to acid, alkali, or organic compounds.
In this retrospective study, a total of 21 patients suffering occupational chemical burns, came
to the emergency room at the University General Hospital of Alexandroupolis, from 2008 to
2010; 76.2% were workers, 19% were farmers, and 4.8% were desk officers. The majority of
burns were due to exposure to acid (61.9%). Upper extremities were the most frequently
injured area followed by the lower extremities and thorax. None of the patients needed further
hospital care, but in the follow-up, four of the patients suffered keloid. Proper surgical
treatment at the emergency room decreases the length of hospital stay for patients who suffer
chemically induced burns.
13. Porpodis K, Konoglou M, Zarogoulidis P, Kaimakamis E, Kontakiotis T, Papakosta D, Zervas V,
Katsikogiannis N, Courcoutsakis N, Mitrakas A, Touzopoulos P, Karanikas M, Zarogoulidis K,
Markopoulou A. Pulmonary thromboendarterectomy after treatment with treprostenil in a
chronic thromboembolic pulmonary hypertension patient: a case report. Int J Gen Med.
2011;4:767-72. DOI: 10.2147/IJGM.S26494) Epub 2011 Nov 8 PMID: 22114523 [PubMed]
Abstract: In recent years, there has been a major advance in the treatment of pulmonary
hypertension. New medications are continually added to the therapeutic arsenal. The
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